Melvin Leonard "Mike" Mazzera (January 31, 1914 – December 17, 1997) was an American professional baseball player.

In an 11-year career, Mazzera participated in five Major League seasons: four with the St. Louis Browns and one with the Philadelphia Phillies.

[3] In 1933, Mazzera began his professional baseball career playing for the C-level San Antonio Missions.

In 1935, Mazzera participated in 154 games for the San Antonio Missions while making his Major League debut for the St. Louis Browns on September 9, 1935.

In 86 games played, Mazzera batted for a .279 average with six home runs and twenty-five strikeouts, helping the Browns to finish seventh in the American League with a 55–97 record.