Part of the Gamo Gofa Zone, Melokoza is bordered on the south by Basketo special woreda, on the southwest by the Debub (South) Omo Zone, on the northwest by the Konta special woreda, on the north by the Dawro Zone, and on the east by Demba Gofa and Geze Gofa; the Omo River defines its northwestern boundary separating the woreda from Konta and the Dawro Zone.
Food crops in Melokoza include enset, sweet potatoes and yams, maize and horse beans, while coffee and the cardamom-like spice aframomum are significant cash crops.
[2] A September 2007 landslide in Melokoza was reported to have killed three people, displaced 42 households, and damaged 15 hectares of crops.
[5] However, Ralph Siebert's local research in 1995 led him to believe that this woreda was predominantly inhabited by the Goffa people, although in the same report he notes that "Laha is one of the main places in the Melo area, and the variety [of language] spoken there is similar to Gofa".
[6] Concerning religious beliefs, the 1994 census reported that 37.47% of the population said they practiced Ethiopian Orthodox Christianity, 29.04% were Protestants, and 28.03% observed traditional religions.