Melorheostosis is a medical developmental disorder and mesenchymal dysplasia in which the bony cortex widens and becomes hyperdense in a sclerotomal distribution.

[5] The disorder can be detected by radiograph due to thickening of bony cortex resembling "dripping candle wax."

[6] The disorder tends to be unilateral and monostotic (i.e. affecting a single bone), with only one limb typically involved.

Melorheostosis can be associated with pain, physical deformity, skin and circulation problems, contractures, and functional limitation.

In severe cases amputation has been performed when conservative measures such as physical therapy and regional anesthetics have been ineffective.