Membrane steroid receptors (mSRs), also called extranuclear steroid receptors, are a class of cell surface receptors activated by endogenous steroids that mediate rapid, non-genomic signaling via modulation of intracellular signaling cascades.
[1][2][3][4] mSRs are another means besides classical nuclear steroid hormone receptors (SHRs) for steroids to mediate their biological effects.
[1][2][3][4] SHRs can produce slow genomic responses or rapid, non-genomic responses in the case of mSRs.
[5] Known groups of mSRs, by ligand, include:[a] In addition, PDIA3 is a membrane receptor for the secosteroid calcitriol, the activated form of Vitamin D.[7]
This article about a biochemical receptor is a stub.