The acclamation references the memorial aspect of the Eucharist, taught by Jesus at the Last Supper: "Do this, as often as you drink it, in remembrance of me" (1 Corinthians 11:25).
In the Syriac form of this liturgy, after the Words of Institution, to which the people respond with "Amen" after the formula for the blessing of the bread and again after the formula for the blessing of the chalice, the priest celebrant says: "Do in remembrance of Me when you partake of this sacrament, commemorating My death and My resurrection until I come."
The people then respond with the acclamation: "Your death, our Lord, we commemorate, Your resurrection we confess and Your second coming we wait for.
For every time you eat of this bread and drink of this cup, you proclaim My Death, confess My Resurrection, and remember Me till I come.
[10] The three acclamations given in the Roman Missal are, in the official English translation, as follows: We proclaim your Death, O Lord, and profess your Resurrection, until you come again.
Before the 1969 revision of the Roman Missal, the phrase mysterium fidei was included in the formula of consecration of the wine spoken inaudibly by the priest,[12] appearing as follows (here accompanied by an unofficial English translation):[13]
An alternative memorial acclamation permitted in Ireland, "My Lord and my God", was disapproved of by Pope Paul VI for seemingly concentrating on the real presence of Christ in the Eucharist rather than on Eucharistic sacrifice as a whole, but even this may be interpreted in the same sense, since it is a repetition of what in John 20:28 refers to Christ as risen and as still bearing the marks of his suffering.
[15] Lutherans have the Memorial Acclamation:[16] For whenever you eat this bread and drink this cup, you proclaim the Lord’s death until He comes.