Mercy moved its Psychiatric Services into a totally renovated area in 2009 and opened the region's only Autism Center in July, 2010.

In 1885 St. Joseph's Sanitarium was opened on the edge of the city, becoming the first mental health facility in the area.

The school was phased out when it merged with the Area One (now Northeast Iowa Community College) nursing program, and the last class graduated in 1975.

In 1976 the hospital became part of the Farmington Hills, Michigan based Mercy Health Services.

[citation needed] The trauma center is staffed by doctors who are all board certified in emergency medicine.

The hospital's ER has been designated by the state of Illinois as a level II trauma center and as a recognized pediatric emergency department.

In addition to the Dubuque trauma center, the Dyersville facility also operates an emergency department.