Merenre Nemtyemsaf II (died c. 2213 BC) was an ancient Egyptian king, the sixth and penultimate ruler of the 6th Dynasty.

Merenre Nemtyemsaf II is attested on the 4th line, column 6 of the Turin canon, a king list redacted in the early Ramesside Period.

[9] Nemtyemsaf II is also attested on the 39th entry of the Abydos King List,[9] which dates to the reign of Seti I and constitutes one of the best preserved historical records for the end of the Old Kingdom and beginning of the First Intermediate Period.

A later historical source also records the existence of Nemtyemsaf II: indeed he is mentioned in Manetho's Aegyptiaca, a history of Egypt written in the 3rd century BC.

It is now recognized that the name "Nitocris" is a result of conflation and distortion from the name of a real male pharaoh, Neitiqerty Siptah, who succeeded Nemtyemsaf II.