Located on the bank of the Kama river, he site of the current Meshkov mansion was historically occupied by several buildings.

After the 1842 fire the site sat vacant for several decades until 1877, when prominent local industrialist Nikolai Meshkov purchased the lot and surrounding lands.

Meshkov had been appointed as the head of a steamship company in 1875, and so was interested in investing in Perm, a regional hub for trade.

Turchevich rebuilt the mansion in the style of Art Nouveau with classical overtones, with the house being adorned with decorative arches, Corinthian colonnades, and balconies.

Meshkov did not always occupy the residence, and as such parts of the building were used to house offices for a local shipping company.