[10] In March 2019, former politician Melissa Bean left JPMorgan Chase to join Mesirow as chief executive officer of their wealth management division.

[11] Mesirow completed financing for a new United States Department of Veterans Affairs clinic in Ponce, Puerto Rico in April 2019.

[12] In February 2020, Mesirow bought the Las Vegas Raiders headquarters and practice facility in Henderson, Nevada for $191 million in a sale-and-leaseback.

Brown was named chief executive officer in June 2022, replacing Richard S. Price and becoming the company's first female CEO.

[22] In October 2023, Creative Planning acquired Mesirow's corporate retirement advisory services division, which had approximately $13 billion in assets under management.

[26] From 2019 to 2023, Mesirow received a top score of 100 on the Human Rights Campaign Foundation's Corporate Equality Index.

[30] Mesirow was named to the Barron's list of top 100 registered investment adviser firms from 2021 to 2024, most recently ranking 41st.

[31] In 2022, Mesirow was ranked 13th on the Crain's Chicago Business list of top 25 financial services firms by assets under management.