Messers Run is a tributary of Catawissa Creek in Schuylkill County, Pennsylvania, in the United States.

The creek is a High-Quality Coldwater Fishery and Class A Wild Trout Waters in some places.

[1][2] It flows southwest for several tenths of a mile before entering a valley and turning west-southwest.

In East Union Township, the stream turns northwest and receives the tributary Negro Hollow.

The stream then turns northwest and flows for slightly less than a mile until it reaches its confluence with Catawissa Creek.

[1] Messers Run joins Catawissa Creek 33.90 miles (54.56 km) upstream of its mouth.

[2] The air temperature in the vicinity of Messers Run 3.94 miles (6.34 km) upstream of its mouth was measured to be 24 °C (75 °F) at 3:40 P.M. on July 23, 1997.

The air temperature in the vicinity of the stream was measured to be 23 °C (73 °F) at 4:20 P.M. on July 23, 1997, at a point 0.50 miles (0.80 km) upstream of its mouth.

[2] The specific conductivity of the waters of Messers Run 3.94 miles (6.34 km) upstream of its mouth is 223 micromhos.

This rock formation consists of siltstone, sandstone, grayish-red shale, and conglomerate.

However, areas that are on the Pottsville Formation are scattered throughout the watershed, mainly along its southern and northern edges.

This rock formation is especially common in the sub-watershed of Negro Hollow and near the upper reaches of "Trib 27609 To Messers Run".

The Pottsville Formation contains claystone, limestone, conglomerate, shale, and gray sandstone.

The Leck Kill soil occurs in the northwestern part of the watershed (in its lower reaches).

Both of the unnamed tributaries of Messers Run are surrounded by such areas for the majority of their length.

[4] Messers Run has a width of 2.3 metres (7.5 ft) upstream of the Lofty Reservoir.

[3] The stream passes through the United States Geological Survey quadrangles of Conyngham and Delano.

No part of Messers Run upstream of the Lofty Reservoir is within 1,600 feet (500 m) of a road.

[2] The Mahanoy Water Company sought permission to construct a dam on Messers Run as early as 1913.

[7] Messers Run was surveyed once by the environmental services branch of the Pennsylvania Fish and Boat Commission.

[2] Messers Run is considered by the Pennsylvania Department of Environmental Protection to be a High-Quality Coldwater Fishery, as is its tributary Negro Hollow.

Both Messers Run (from Lofty Reservoir downstream to Blue Head Reservoir) and Negro Hollow (between its headwaters and its mouth) are also considered by the Pennsylvania Fish and Boat Commission to be Class A Wild Trout Waters.

Upstream of the Lofty Reservoir, there are two species of fish inhabiting the stream: brook trout, eastern blacknose dace.

[2] A 1997 report stated that Messers Run was a poor site for angling upstream of the Lofty Reservoir.

[2] Additionally, the Pennsylvania State Game Lands Number 308 are in the stream's watershed.