Born in San Francisco and raised in Los Angeles, Rosenberg graduated from Hollywood High School in 1930, after skipping three grades.
[2] From the mid-thirties to the late forties, Rosenberg was head of the literary department at the Berg-Allenberg talent agency, and worked with such writers as Christopher Isherwood, Bertold Brecht, and Raymond Chandler.
[8] She returned to working as a talent agent in 1960, and represented actors including Robert Redford and James Garner.
In 1963 she created Breaking Point, a spinoff of Ben Casey which starred Paul Richards as a resident psychiatrist at a fictional New York City hospital.
In her later years, Rosenberg was an enthusiastic amateur photographer whose works were exhibited at the Peter Fetterman Gallery in Santa Monica.