Federal Highway 261 (Carretera Federal 261) is a Federal Highway of Mexico.

It connects Campeche City with Umán in Yucatán (230.83 kilometres (143.43 mi)) and Mérida with Progreso (35.04 kilometres (21.77 mi)); it also serves as a bypass of the latter city (6.5 kilometres (4.0 mi)).

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