Highway 95D is among the most important toll roads in the country, serving as a backbone for traffic out of Mexico City toward Morelos and tourist destinations in Guerrero.

The other is by taking the 7-kilometre (4.3 mi) Second Story Interconnection (Interconexión Segundo Piso), which is a direct flyover from the Autopista Urbana Sur following Viaducto Tlalpan and the Highway 95D route as it hugs the side of the Heroico Colegio Militar.

As it heads south, it passes a rest stop at Parres, a small town within Mexico City limits, with amenities such as a Federal Police booth, restaurants and convenience stores.

The road turns east and then makes a hairpin curve dubbed La Pera (The Pear), bending for the southwest and toward Cuernavaca.

Highway 95D enters the Cuernavaca metropolitan area east of the campus of the Universidad Autónoma del Estado de Morelos, with interchanges at the Glorieta La Paloma de la Paz monument, Avenida Vicente Guerrero, and Avenida Río Mayo near the Plaza Diana shopping center as it wraps east around the Cuernavaca metropolitan area; its interchange with the local street Plan de Ayala marks the end of Mexican Federal Highway 160.

[9] Just three months after opening, a section of the road, swallowing a car and claiming two lives; the SCT blamed erosion and a sewer backed up with trash and water from recent rains.

[18] In 2007, Gutsa, a contractor selected to maintain and rehabilitate a 60-kilometer stretch of the highway, failed to meet its contractual obligations, which resulted in the contract being terminated and the SCT taking control of the road improvements.

The tunnel is 2,953 metres (9,688 ft) long and was designed to reduce the travel time from Acapulco to Mexico City by 25 minutes, allowing motorists to avoid local traffic.

It was built by a consortium of Grupo Mexicano de Desarrollo, Empresas ICA (Ingenieros Civiles Asociados), and Triturados Basálticos y Derivados.