The colony of Spanish Formosa was held until 1642 and was administered by the Viceroy of New Spain in Mexico City.

[1] Beginning in 1949, Mexico maintained diplomatic relations with the Kuomintang government of the Republic of China.

That same year, a high-level Mexican government official attended the 42nd National Day of the Republic of China.

[6] In 1994, Taiwanese Prime Minister Lien Chan paid a visit to Mexico and met with Mexican President Carlos Salinas de Gortari and presidential candidate Ernesto Zedillo.

[6] In November 2002, Taiwanese Representative of the President, Yuan T. Lee, visited Los Cabos, Mexico to attend the APEC summit.