Established in 1968, the program is based in Differdange Castle in southwestern Luxembourg and enrolls around 125 students each semester from Miami and other American universities.

Charles Ray Wilson, university provost, conceived the project of an international campus in the 1960s.

John E. Dolibois, at the time Vice President for Development and Alumni Affairs, was the first to suggest his native Luxembourg and was instrumental in establishing the campus, which took his name in 1988 for his efforts.

[3] MUDEC offers continuing classes pertaining to students' studies at the main Miami University campus, typically in architecture, business, French, German, history, and political science.

Students live in homestays with Luxembourgish host families, and are encouraged to travel throughout Europe over weekends as well as through university-led study programs.