Michael II Komnenos Doukas, Latinized as Comnenus Ducas (Greek: Μιχαήλ Β΄ Κομνηνός Δούκας, Mikhaēl II Komnēnos Doukas), often called Michael Angelos in narrative sources, was from 1230 until his death in 1266/68 the ruler of the Despotate of Epirus, which included Epirus in northwestern Greece, the western part of Greek Macedonia and Thessaly, and western Greece as far south as Nafpaktos.

His domain was reduced to the environs of the city, and his family's core territories in Epirus and Thessaly, as well as Dyrrhachium and Corfu, while his brother Constantine Komnenos Doukas in Aetolia and Acarnania recognized his suzerainty.

[8] Michael II secured the support of local notables by marrying Theodora Petraliphaina, and established a close relationship with the Empire of Nicaea.

In 1238, Michael was visited by the Nicaean Patriarch Germanus II and in 1249 he received the court dignity of despotes from Emperor John III Doukas Vatatzes.

[12][13] Michael II's relations with Nicaea ensured his neutrality during the conflict in which John III Doukas Vatatzes conquered Thessalonica and penetrated into northern Greece in 1244–46.

Demetrios Angelos Doukas, who had ruled the city after his elder brother John's death in 1244, was captured and exiled to Bithynia, while Thessalonica and all of Macedonia were placed under the governance of the Grand Domestic Andronikos Palaiologos.

The pro-Nicaean historians consider this stance an indication of his inherent untrustworthiness, but a major factor was the influence of his uncle, Theodore, who remained safely ensconced in his stronghold of Vodena.

With his sons out of the picture, Theodore turned to the sole surviving member of his family who could claim Thessalonica and thwart Nicaea's plans, especially as Vatatzes, with no threats on his other borders, was mobilizing to capture Constantinople.

The stalemate was broken when two Epirote generals, John Glabas and Michael's brother-in-law Theodore Petraliphas, defected to the Nicaeans, followed shortly after by the ruler of Kruja, Golem.

The treaty, concluded at Larissa, stipulated that Michael would cede not only the fortresses he had recently captured but all his remaining holdings in Macedonia, while Kruja would come under Vatatzes' suzerainty.

While the Nikephoros received the title of Despot and soon allowed to return to Epirus, Theodore was moved as a prisoner to Asia Minor where he died shortly after, in ca.