While his birthplace in Ireland is undetermined, various locations (such as Ballinoulart, Castleannesley or in Kilnew, County Wexford) are documented as possibilities.
He was ordained a priest in 1785 at Wexford after completing hedge school in Oulart.
After continuing his Theology and Philosophy studies at the Irish College in Bordeaux in France, his first parish was at Ballycanew.
[1] Murphy joined the Rebellion on 27 May 1798 following the vandalism of his church by yeomanry, in defiance of the strictly anti-United Irishmen stance of the Hierarchy of the Catholic Church in Ireland.
Murphy was attacking a gun position on horseback at the Battle of Arklow on 9 June 1798 when he was killed by gunfire.