He then began his professional career in the 2012–13 season, with Filathlitikos, playing in the Greek 2nd Division.
[2] On 29 July 2015, he was loaned to the Greek club Rethymno Cretan Kings, where he spent two seasons.
[3] With AEK, he won the Greek Cup title, in 2018, as well as the FIBA Champions League's 2018 championship.
On June 4, 2019, Kamperidis returned to the Rethymno Cretan Kings, signing a two-year contract.
[5] On August 2, 2021, Kamperidis signed with PAOK, joining his younger brother Georgios.