Michalis Polytarchou (Greek: Μιχάλης Πολυτάρχου; born June 23, 1983) is a Greek professional basketball player who plays for Dafni Dafniou of the National League 2.

Polytarchou began his career with the team of his homeland, Pannaxiakos, playing in the regional leagues of Cyclades.

Later, he moved to Trikala 2000, Argonaftis Rafinas B.C., Ardittos B.C., and Ierapetra B.C., playing in the lower leagues of Greek Basketball.

After his release from AEK Athens, he signed a two-year contract with Peristeri.

After he had originally renewed his contract with Peristeri through 2019, the two sides mutually agreed to part ways on September 30, 2018.