He initially worked as a self-employed pianist and later went to Marseille to study music.

During the Interwar period and the 1950s, he was extremely prolific, writing over 700 songs in different styles (tango, waltz, serenades, folk, laiko, romances amongst others).

He co-worked with some of the most well-known lyricists (such as Alekos Sakellarios) and singers (Sofia Vembo, Nikos Gounaris, Tony Maroudas, Kalouta sisters, Stella Greka) of the time.

Souyioul had four children: daughters Maria, Iro and Aliki and son Thanos.

Thanos (born 1942) was an actor (who worked alongside famous actress Aliki Vougiouklaki in films such as Maiden's Cheek and Alice in the Navy) and musician in a well-known Greek pop band of the early 1960s, The Juniors.