become a standard in biomaterials engineering and for fundamental research on cellular biology by mean of soft lithography.
[1] In cellular biology, micropatterns can be used to control the geometry of adhesion and substrate rigidity.
[2] [3] Micropatterns can be made on a wide range of substrates, from glass to polyacrylamide and polydimethylsiloxane (PDMS).
Advanced custom micropatterning[4] allow precise and relatively rapid experiments controlling cell adhesion, cell migration, guidance, 3D confinement and microfabrication of microstructured chips.
[5] Using advanced tools, protein patterns can be produced in virtually unlimited numbers (2D/ 3D shapes and volumes).