The Mid-State Athletic Conference (MSAC) is a junior college conference located within Region III of the National Junior College Athletic Association (NJCAA).

Conference championships are held in most sports and individuals can be named to All-Conference teams.

After collaboration with other conferences already formed within Region III, Mr. Hinkle drafted MSAC by-laws.

The original members were: In the early 1990s, SUNY Canton was added as well as Corning Community College.

Columbia-Greene Community College joined from the Mountain Valley Athletic Conference for the 2016-17 school year.