Middle Creek is a tributary of the Tahltan River, part of the Stikine River watershed in northwest part of the province of British Columbia, Canada.

Middle Creek's watershed covers 49.6 km2 (19.2 sq mi),[6] and its mean annual discharge is estimated at 0.449 m3/s (15.9 cu ft/s).

[6] The mouth of Middle Creek is located about 20 km (12 mi) north of Telegraph Creek, British Columbia, about 75 km (47 mi) southwest of Dease Lake, British Columbia, and about 197 km (122 mi) east of Juneau, Alaska.

Middle Creek's watershed's land cover is classified as 45.2% shrubland, 30.8% conifer forest, 21.4% mixed forest, and small amounts of other cover.

[8][9] Middle Creek originates on the southeast edge of the massive Level Mountain shield volcano, about 35 km (22 mi) south-southeast of Meszah Peak, the highest peak of the Level Mountain Range, a cluster of bare peaks on the summit of Level Mountain.