It connects the pons to the cerebellum, with fibres originating from the pontine nuclei, and travelling to the opposite cerebellar hemisphere.

[2] The trigeminal nerve (CN V) arises from the lateral pons very close to the middle cerebellar peduncle.

[3] The middle cerebellar peduncle is supplied by the anterior inferior cerebellar artery (AICA), as well as smaller branches from the basilar artery.

[4] Diffuse intrinsic pontine glioma may spread from the pons into the middle cerebellar peduncle.

[5] This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918) 2° (Spinomesencephalic tract → Superior colliculus of Midbrain tectum)