The Middleton-Pinckney House is a historic three-story home built on a raised basement at 14 George Street, Charleston, South Carolina in the Ansonborough neighborhood.

[3] Frances Motte Middleton (a daughter of Jacob and Rebecca Brewton Motte and widow of John Middleton) began construction of the house in 1796 after purchasing a second lot adjacent to one bought by her father on George St.

One exception occurred in 1816, when the family resided on Legare Street, perhaps to permit the reworking of the house in the then-popular Regency style.

The house remained a private residence until Jesse W. Starr Jr. bought it from Mrs. Elliott's estate in 1879 and resold it to the Water Works Company of Charleston in 1880.

The City of Charleston donated the house to the festival in 2002, which undertook a rehabilitation of the property.