The section between Minoh-kayano and Esaka is owned and operated by Kita-Osaka Kyuko Railway (北大阪急行電鉄, Kita Osaka Dentetsu), but is seamless to the passengers except with respect to fare calculations.

Since 2016, it is also possible for Midōsuji Line rolling stock to access Midorigi Depot on the Yotsubashi Line via pointworks before Daikokuchō station, after heavier repairs and maintenance of all third-rail-powered Osaka Metro rolling stock were consolidated there.

Its construction was partly an effort to give work to the many unemployed people in Osaka during the early 1930s.

The initial tunnel from Umeda to Shinsaibashi, as well as the Umeda depot, were constructed entirely by hand and opened in 1933 after being initially plagued by cave-ins and water leakage caused by the poor composition of the earth below northern Osaka and the equally poor engineering skills of the work crew.

[7] The first cars were hauled onto the line by manpower and pack animals from the Government Railway tracks near Umeda.