The league spans primarily the eastern and central portions of the Midwestern United States.

[5] Cedar Rapids Inferno join the MWPL on October 9, 2019 making it the fourth member team.

Conrad is the co-founder and president of Union Dubuque F.C., one of the league's charter members.

[12] The league was set to kick off in spring 2020; however, the season was cancelled due to the COVID-19 pandemic in the United States.

[16][17] On September 3, 2020, the MWPL entered a partnership agreement with the National Independent Soccer Association, a USSF Division 3 professional league, which includes pathways for both players and clubs to go fully pro.

Rules for classification: P) points; (GP) games played; (GD) goal differential; (C) Champion The first season with 3 divisions in it.

Rules for classification: P) points; (GP) games played; (GD) goal differential; (C) Champion The first season with 4 divisions.

Rules for classification: P) points; (GP) games played; (GD) goal differential; (C) Champion The first season with 5 divisions in it.