Mifflinburg is a borough in Union County, located in the Susquehanna River Valley of central Pennsylvania, United States.

Major tourist attractions include The borough is situated on lands that were originally granted in 1769 to the veteran officers who served under Colonel Henry Bouquet during Pontiac's War (1763-1766) in lieu of payment for their service and ultimate victory at the Battle of Bushy Run in defense of Fort Pitt (Pittsburgh).

In 1782 or 1783, Elias and Catharina Jungman (Youngman) and their children, came from Fort Augusta (now Sunbury) Pennsylvania to the Buffalo Valley with 8 other families to settle on land purchased by Elias from Catharina's father, George Nagle.

In the summer of 1792, Elias surveyed and divided the land into 60' by 120' plots that were sold to other adventurous settlers, many of them German, and the village of Mifflinburg was formed (common nomenclature was attributed to the town being named "Youngmanstown", as was historically the case, but was Mifflinburg in the deeds as early as 1792).

In 1797, George Rote (Rhoade) laid out a village just east of Youngmanstown, known as Greenville or Rotestown (common nomenclature).

The combined village was named Mifflinburg, in honor of Thomas Mifflin, the first Governor of Pennsylvania after the 1790 Constitution.

According to the United States Census Bureau, the borough has a total area of 1.8 square miles (4.7 km2), all land.

Major employers include Weis Markets (a supermarket), Mifflinburg Area School District, CVS, Cole's Hardware, Ritz-Craft (a manufacturer of modular homes), and Yorktowne (a cabinetry manufacturer).

In 2005, Yorktowne management made the decision to move most of the Mifflinburg operations to Danville, Virginia, rather than comply with new air pollution regulations in Pennsylvania.

[13] Major tourist attractions include Mifflinburg's business district is centered on Pennsylvania Route 45.

The general-aviation Penn Valley Airport (IATA: SEG) is located 15 miles southeast.