The domain was centered at Mikami jin'ya, located in what is now the city of Yasu in Shiga Prefecture.
[1] The Endō clan ruled the 24,000 koku Gujō Domain in Mino Province from the start of the Tokugawa shogunate.
However in light of the services the early Endō clan had given to Tokugawa Ieyasu, Shogun Tokugawa Tsunayoshi agreed to preserve the clan name, which was assigned to the eldest son of one of his hatamoto, Shirasu Tadayasu, who was married to the daughter of one of his concubines, Oden-no-kata.
[1] The 5th daimyō, Endō Tanenori, served as wakadoshiyori and supervised the reconstruction of the Nishi-no-maru enclosure of Edo Castle, for which he was awarded an increase in kokudaka to 12,000 koku.
His successor and final daimyō, Endō Taneki, was Bugyō over the Kōbusho (shogunal military academy) from 1863 and participated in the First Chōshū expedition of 1864.