A few months later, he was appointed CEO of Joost,[10][11][7][12][13][14] an Internet startup focused on online TV which was founded by Skype founders Niklas Zennstrom and Janus Friis.

[17] At Index Ventures, Volpi invests in early-stage companies, primarily across autonomous driving, enterprise and open source.

[18] Volpi has served on the boards of Index portfolio companies Big Switch Networks, Blue Bottle Coffee (acquired by Nestle),[19] Confluent Software, Elastic, Hortonworks, Lookout, Pure Storage, Sonos, Ubiquity6, and Zuora.

[20][21] During Volpi's time at Index, the grew its office in San Francisco to an equal presence on both sides of the Atlantic Ocean.

Volpi serves sits on the board of Castilleja School, an independent school for girls grades six through twelve in Palo Alto, California,[29] and is a Global Advisory Board Member at Knight-Hennessy Scholars, an international graduate-level scholarship program for study at Stanford University.

[30] He served on the board of Witness, a non-profit organization that uses video to find human rights violations,[31] and on the advisory council for the Stanford University Graduate School of Business.