He was born in Cerignola, but began his acting and performing career in France, in the musical Les Nouveaux Nomades by Claude Barzotti and Anne-Marie Gaspard.

Discovered in Belgium by Alec Mansion (member of Léopold Nord & Vous band), Loconte worked as an artistic director in the studio La Chapelle in Waimes.

At the age of twenty-one, he met singer Rita Pavone, who along with Teddy Reno declared him winner of the Festival des Inconnues during a broadcast on RAI 2.

He took part in the show Mozart, l'opéra rock, touring France, Switzerland and Belgium from September 2014, accompanied by a symphony orchestra from Kyiv.

In autumn 2016, Mikelangelo played Monsieur Loyal in Jean-Jacques Thibaud's musical Timéo, directed by Alex Goude, at the Casino de Paris from September 16, 2016 to January 8, 2017, then on tour throughout France.

He regularly takes part in musical charity events (often in aid of children) such as Une Nuit à Makala with numerous artists, for the association Les voix de l'enfant with the single Je reprends ma route in 2013 and with the artists' collective Les grandes voix des comédies musicales chantent pour les enfants hospitalisés alongside Renaud Hantson, Pablo Villafranca and Lââm for the single Un faux départ, as well as the Nuit des Hits in aid of the association Enfant Star et Match which helps sick children.