[12] Radisic started her career as a research assistant at McMaster University and MIT before working as a postdoctoral associate at Harvard-MIT Division of Health Science and Technology.

Radisic was the first author of a highly cited paper in PNAS where she successfully generated beating heart tissues from embryonic stem cells via electrical stimulation.

[18] Radisic has also worked on other biomaterials such as moldable elastomeric polyester-carbon nanotube scaffolds for cardiac tissue engineering that will promote survival and localization of the cardio-myocytes injected into the infarcted myocardium.

[20] Her lab designed micro-fabricated cell culture systems with built-in electrodes and defined groove and ridge heights for simultaneous application of field stimulation and contact guidance cues, in order to understand interactive effects of multiple physical stimuli.

Radisic and her team developed a microfabricated system for generating 3D, aligned beating cardiac tissue (Bio-wire) from human pluripotent stem cells (hPSC) derived cardiomyocytes.