The Mill Creek Generating Station is a coal-fired power plant owned and operated by Louisville Gas & Electric in the Kosmosdale neighborhood of Louisville, Kentucky.

Construction on the plant began in 1968 to meet growing energy demand in the Louisville area, according to the utility.

Mill Creek Generating Station is LG&E's largest coal-fired power plant.

In 2024, the utility began construction on a 640-megawatt natural gas combined-cycle generating unit at the plant, expected to begin operations in 2027.

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