Millitome design and usage was developed by the HIVE MC-IU Team, Indiana University (PI: Katy Börner; NIH Award No: OT2OD026671) and members of the Cyberinfrastructure for Network Science Center (CNS) for the Human Reference Atlas project,[1] which is part of the U.S. National Institutes of Health Common Fund’s Human Biomolecular Atlas Program (HuBMAP).
[3] A millitome has an associated digital data package that includes an STL file, a spreadsheet for assigning spatial locations to HuBMAP IDs, and a metadata file with information about the size, dimensions, donor sex, and laterality of the reference organ for which the millitome is fitted.
The procedures outlined here describe how millitomes are generated and how spatial locations for each slice or cube are retained in the Human Reference Atlas.
[7] The resulting 3D model has two main uses: Using the same 3D geometry for both purposes guarantees that dimensions, proportions and other attributes of a specific millitome match in both the physical and virtual versions.
The Lookup CSV spreadsheet provided as part of the data package lists Millitome IDs that have been pre-assigned to each block in the cutting grid.