Milltown House is a historic building in Strabane, County Tyrone, Northern Ireland.

The two-storey gabled cottage-style house and gate lodge was constructed in c. 1836 for Major John Humphreys (father of Cecil Frances Alexander), agent to the 2nd Marquess of Abercorn (later created, in 1868, the 1st Duke of Abercorn), and was designed by William Vitruvius Morrison.

[1] At the age of fifteen, Irish hymn-writer and poet, Cecil Frances Alexander,[2] moved into Milltown House, with her family.

In 2022 the Education Authority resolved to sell the 8.9 ha (22 acres) site, including Milltown House.

[10] The Derry City and Strabane District Council has resolved to request the Authority preserve the historic building and examine the possibility of transferring it as a community asset.