Milperra, a suburb of local government area City of Canterbury-Bankstown, is located 24 kilometres west of the Sydney central business district in the state of New South Wales, Australia, and is a part of the South Western Sydney region.

The land at Milperra was taken over by George Johnson Jr. After World War I, returning soldiers established poultry farms and vegetable gardens in the area.

It became the Macarthur Institute of Higher Education in 1983, and then became the Bankstown campus of Western Sydney University in 1989.

In September 1984, on Father's Day, members of rival motorbike gangs the Comanchero and the Bandidos had a showdown in the car park of the Milperra Viking Tavern, which is technically located in Revesby.

The M5 South Western Motorway runs along the southern border and Henry Lawson Drive is the other major road through the area.