MATC offers day, evening, weekend and online classes at campuses in downtown Milwaukee, Oak Creek, West Allis, and Mequon as well as an education center in the Walker's Square neighborhood on Milwaukee's near south side.

One of MATC's educational outreach programs is the operation of the two PBS stations serving Milwaukee and southeastern Wisconsin.

In 1992, in partnership with Zenith Electronics and AT&T, Channel 10 produced the nation's first test broadcast of a digital television signal.

[6] Milwaukee Area Technical College traces its roots to a 1911 Wisconsin law whose purpose was to encourage young adults who dropped out of high school to work full-time to continue their education part-time.

Enrollment grew quickly, and in 1920–28, a new six-story building was completed at 6th & State Street–the core of what is now the Downtown campus.