The Milwaukee Hospital in Milwaukee, Wisconsin, United States, was a leader in antiseptic surgery when its surgery rooms opened in 1912, and was also a leader in using x-rays in medicine, having in 1926 the most powerful x-ray machine in the U.S.[1] The complex was added to the National Register of Historic Places in 2006.

In 1884 the hospital built a new building designed specifically for patient care.

Dr. Nicholas Senn was on staff from 1879, internationally recognized for his use of antiseptic procedures to explore the pancreas and intestines.

This 5-story building, designed by Meyer J. Sturm of Chicago, is the oldest surviving part of the complex.

[1] Its original enclosing iron fence atop a rough cut Waukesha blue stone wall dates from 1903, with the wrought produced by German immigrant Casper Hennecke and marked "C. Hennecke Co. Iron & Wire Works, Milwaukee, Wis".