During the daytime, the station is served by two "Local" (all-stations) trains per hour in each direction between Ogawamachi and Yorii.

Outbound travelers could not use automatic ticket gates, so passengers had to get certification upon boarding on the trains (ja:乗車証明書) until Tojo Line's timetable was revised 13 March 2021.

In November 2018, in conjunction with Honda Motor's decision to relocate its factory from Sayama to Yorii, Tōbu Railway was approached to build a station to help alleviate anticipated traffic congestion on Japan National Route 254.

Construction began in June 2019 and the new station opened on 31 October 2020.

[5][6] Media related to Minami-Yorii Station at Wikimedia Commons