The Oliy Majlis exercises legislative authority over the Ministry of Defense through the Government of Uzbekistan, which is nominally responsible for maintaining the armed forces at the appropriate level of readiness.

On September 6, 1991, the newly elected president Islam Karimov signed a decree establishing the Ministry of Defense, being originally named as the main military department of the Uzbek SSR.

In August 1998, at a meeting of the National Security Council under the President of Uzbekistan, it was decided to separate the General Staff from the Ministry of Defense.

Different special units in the armed forces include the following: On 24 October 2012, the Public Council of the Ministry of Defence was established.

[11] Military districts of the armed forces are under the jurisdiction of the defense ministry, with their headquarters being the center of their regions of which they are responsible for.