The miR-26 microRNA is a small non-coding RNA that is involved in regulating gene expression.

[1] Pre-miR-26 with stem-loop structure is processed into mature miR-26 by a series of enzymes of intranuclear and intracytoplasm.

miR-26 expression is induced in response to hypoxia and upregulated during smooth muscle cell (SMC) differentiation[5] and neurogenesis.

[6] Moreover, miR-26 is consistently down-regulated in a wide range of malignant tumors, such as hepatocellular carcinoma,[7] nasopharyngeal carcinoma,[8][9] lung cancer,[10] and breast cancer.

[14] Elevated expression of miR-26b has been reported in pituitary tumor[15] and bladder cancer.