This mission was part of the Shuttle–Mir Program, in which three American astronauts flew aboard the station during Mir EO-24.

Note: Léopold Eyharts joined the Soyuz TM-26 crew on the way home from Mir, after launching with Soyuz TM-27 crewmembers Talgat Musabayev and Nikolai Budarin at the end of Mir EO-24.

Foale arrived aboard Mir during the EO-23 mission, and was transferred to the EO-24 crew when the expeditions changed.

Thomas remained aboard Mir as part of the EO-25 crew after the end of EO-24.

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