The title of her PhD thesis was "Variational Object-Oriented Programming Beyond Classes and Inheritance".
[9] In 2019, she received an ERC Proof of Concept-Grant for the project "Programming Abstractions for Applications in Cloud Environments (PACE)".
[10] She is a member of various committees, including the Computer Science Review Board of the German Research Foundation DFG,[11] the international START/Wittgenstein Jury of the Austrian Science Fund[12] and the Executive Committee of SIGPLAN - Special Interest Group for Programming Languages - of the Association for Computing Machinery (ACM).
In addition, Mezini is one of the representatives in the Quadriga to the National Pact for Cybersecurity[13] and in 2020 was appointed to the ERC Scientific Council Search Committee by the European Commissioner for Innovation, Research, Culture, Education and Youth.
[14] She was named as an ACM Fellow, in the 2024 class of fellows, "for contributions to programming languages and software analysis with applications in distributed systems, cybersecurity, and artificial intelligence and for contributions to learning-based code completion".