She has acted in other films and in several television series, the latter including a recurring role as Sister Helen on the Fox/WB sitcom Grounded for Life.
She appeared on stage alongside Shelley Long, George Wendt, Andrea Martin, Catherine O'Hara, and James Belushi.
In 1996–1997, she was a regular cast member in Malcolm & Eddie, playing Kelly, a bar owner and landlord to the main characters, for the program's first season.
As a voice artist, Flynn has been featured in The Land Before Time series, as Grandma Longneck after Linda Gary's death in 1995; on both Taz-Mania and What-a-Mess as the title character's mother, Jean; as Poil in The Spooktacular New Adventures of Casper; and in Family Guy as well as Rudy's mother, Millie Tabootie on the Nickelodeon show, ChalkZone and Aunt Vera on the Cartoon Network show, Ben 10.
(1988), Stealing Home (1988), Lonely Hearts (1991), Evolution (2001), Wieners (2008), About Fifty (2011) and Bucky Larson: Born to Be a Star (2011).