Maria Wilhelmina Johanna "Mirjam" Melchers-Van Poppel (born 26 September 1975 in Arnhem, Gelderland) is a female former racing cyclist from the Netherlands, married to former sprinter Jean-Paul van Poppel.

She was one of the leading cyclists in the world, having held the UCI number one ranking[when?]

In 2003, she won the GP Feminas Castilla y Leon round of the World Cup and finished third overall in the series behind Nicole Cooke and German sprinter Regina Schleicher.

Melchers also finished first in the Damesronde van Drenthe and the Emakumeen Bira, before bringing her season to a close with a silver medal at the world championship road race in Hamilton, Ontario, Canada.

Note: Beginning in 1997, the Union Cycliste Internationale awarded points to riders based on performances in races.