Beginning writing since around 1967, Yamamura was nominated three times for Edogawa Ranpo Award [ja] in 1970, 1972 and 1973,[1] and it was in 1974 when she made a major debut with "Disappeared into the Sea of Melaka" (マラッカの海に消えた, Marakkano Umini Kieta).
[3] Yamamura wrote two TV screen plays before her major debut for a very popular series of detective drama "SWAT: Special Investigation Team" (特別機動捜査隊).
Debuting as a Columbia senior in 1975's Coffin of Flowers (花の棺, Hana no Hitsugi), this character ultimately resettled in Japan as a fashion reporter/photographer, appearing in a total of twenty novels and dozens of short stories.
[11][notes 1] Many years after her death, Nishimura published the biographical novel A Woman Writer (女流作家, Joryū Sakka) with a portrait picture of Misa Yamamura.
[14] In 2006, he further homaged her with his own Coffin of Flowers (華の棺, Hana no Hitsugi); originally serialized in four parts from October 27 to November 17 for weekly magazine Shūkan Asahi, it centered on the legacy of deceased mystery writer Natsuko Emoto, a fictionalization of Yamamura.