Misfits is about a group of young offenders sentenced to work in a community service programme who obtain supernatural powers after a strange electrical storm.

These tweets and other website postings provided additional narrative material and, amongst other things, did not ultimately reveal the identity of a key character who appeared only in episode six.

After the third series, it was announced that Rheon, Thomas, and Socha had left and would be replaced by new cast members Karla Crome, Nathan McMullen and Matt Stokoe, as Jess, Finn, and Alex respectively.

[citation needed] Series 4 began on 28 October 2012, introducing new characters Finn, Jess, Greg, Alex and Abbey.

Kelly Bailey (Lauren Socha)—constantly judged for her class ("chav")—gains the ability of telepathy, Curtis Donovan (Nathan Stewart-Jarrett)—trying to escape a mistake from his past—can rewind time after experiencing an immense sense of regret, Alisha Daniels (Antonia Thomas)—a woman who is extremely comfortable with her sexuality and body—sends people into a sexual frenzy when they touch her skin and Simon Bellamy (Iwan Rheon)—often ignored or not acknowledged—can become invisible.

The group are attacked by their probation officer, Tony, who was driven insane when he acquired his strange powers in the electrical storm and is accidentally killed by Kelly in self-defence.

Other subplots of the series involve Nathan living in the community centre after his mother kicks him out of her house, Alisha and Curtis becoming involved in a relationship, Curtis accidentally changing time so he never split up from his ex-girlfriend Sam, Nathan trying to figure out what his power could be, and Simon's sense of loneliness and isolation from the rest of the group.

After disposing of Sally's body, the delinquents discover the Virtue cult, a group of young people who have begun adopting ultra-conservative behaviour.

Nathan and Simon find that this is the fault of Rachel, a conservative young woman who gained the power of suggestion due to the storm.

As the gang approaches the end of their community service, they are stalked by a mysterious masked man who had previously saved Nathan from the Virtue cult.

Future Simon warns of an unspecified, upcoming crisis and shows that the superpowers will soon become public knowledge– which eventually occurs, only for that timeline to be erased.

Throughout the series, subplots include Nathan discovering his immortality extends to mediumship, Nathan and Kelly's abortive attempt at a relationship, Curtis and Alisha breaking up, Simon slowly becoming more assertive and comfortable with himself, and Curtis starting a relationship with a girl named Nikki, who obtained her teleportation power from a heart transplant.

Elliot, a disillusioned priest, purchases several powers from the same dealer, including Alisha's and Nikki's, and uses them to pose as a reborn Jesus Christ.

While the Misfits are celebrating the fact that they are free from their powers, a follower of "Jesus" holds up the bar where Curtis and Alisha are now working, robs them, and kills Nikki.

Additional minor plots include Simon being manipulated by a cartoonist with a time-altering power and Alisha pushing him not to become "the man in the mask".

Seth breaks up with Kelly and returns to Shannon but quickly realises that anyone resurrected has an all-encompassing desire for blood, essentially rendering them a zombie.

Sally and Tony move on to the afterlife after they reconcile, and Rachel tries to fit in with the culture that she despises by swearing, drinking, trying drugs and having sex, but is unsuccessful.

Curtis and Rudy continue with community service, joined by Finn, an anxious telekinetic, and Jess, a snarky, reserved girl with x-ray vision.

After Curtis's suicide, the gang encounters Abbey, a girl who suffers from amnesia as a result of the storm and later joins the group on community service, and Nadine, a nun with a mysterious secret whom Rudy falls in love with.

Nadine's power is eventually revealed to be the ability to inadvertently summon the Four Horsemen of the Apocalypse when surrounded by anger or violence, which she does after witnessing Alex and Finn arguing over Jess.

Abbey discovers that she is the manifestation of a girl named Laura's power to bring imaginary characters to life, thus explaining why she does not remember anything from before the Storm.

Rudy Two is the victim of a man who has the power to swap ages, forcing him to the brink of death, and Finn finds a new love interest who can download her consciousness into other people's minds, trapping them in a virtual world within her computer.

On the first anniversary of the Storm, Rudy Two and Abbey hold a birthday party which unleashes chaos as people begin to realise that ecstasy reverses their powers.

Karen saves the duo by stabbing Tim in the back, and Rudy Two and all three bury him under the flyover before they, along with Sam, agree to become "proper" superheroes.

The Times gave it four out of five stars, calling it "a new union – salty British street humour with whizz-bang special effects" which should "keep E4's core audience happy".

[15] An online review by The Guardian's Richard Vine said that it was "confident enough to operate in its own universe and set up something new" and that it was aimed at slowly presenting us the "real people" behind a seemingly "tabloid stereotype" of the "ASBO teenager", while also noting that the series Skins also used such a technique for their show.

[16] The Guardian's print reviewer Tim Dowling was enthusiastic, saying: "Misfits is indeed silly – sillier, even, than it sounds – but it's also brilliant: sharp, funny, dark and, in places, quite chilling.

"[17] The Daily Telegraph called attention to Howard Overman's script, which it said, "sparkled from the off, introducing his posse of social outcasts as a bunch of total losers, but each one distinctively and memorably so.

Howard Overman, creator of the UK series, and Murray Ferguson, who produced the original version, were also to be involved with the project.

In November 2018, Vulture noted that Freeform had not made any further announcements in over a year and doubted that the network would find a place for the series in its family-friendly programming.