Japanese writer Yukio Mishima was given his pen name from this station, since his editors were passing through on the way to a meeting with him.

All platforms are connected by an underpass to a central concourse leading to the station building.

[citation needed] The original Mishima Station was opened on 15 June 1896 in the town of Nagaizumi.

On April 25, 1969, Tōkaidō Shinkansen services began serving Mishima Station.

[3] On 27 December 1995, the first and so far only fatality caused by the Tōkaidō Shinkansen occurred at Mishima Station when Yusuke Kawarazaki, a 17-year-old high school student, got caught in a car door, and was dragged down the platform by the leaving train.