Miss Universe Colombia 2021 was the second edition of the Miss Universe Colombia pageant, held at the Chamorro City Hall in Bogotá, Colombia, on October 18, 2021.

Laura Olascuaga of Bolívar crowned Valeria Ayos of Cartagena as her successor at the end of the event.

She represented Colombia at the Miss Universe 2021 competition and placed Top 5.

[1][2] * Voted into Top 13 by viewers.

The Miss Universe Colombia 2022 was appointed by the organization to represent Colombia at Miss Universe 2022.