The school began teaching only freshmen and sophomores, later adding junior and seniors.

Mission Oak is Tulare's newest addition (high school) to the district since Tulare Western opened in 1959.

School colors are purple, black and white, and its athletic teams are nicknamed the Hawks and compete in the six-team West Yosemite League.

The school's mascots are Mo (male) & Mo'Nique (female) Hawks.

The school has won 7 CIF Valley Titles (2015 CIF Central Section Division IV Girls' Basketball Championship, 2015 CIF Central Section Division IV Girls' Softball Championship, 2016 CIF Central Section Division III Girls' Basketball Championship, 2016 CIF Central Section Division IV Girls' Softball Championship, 2019 CIF Central Section Division III Girls' Soccer, 2019 CIF Central Section Division VI Tennis Championship, 2023 CIF Central Section Division III Football Championship.)